William Saliba, Gabriel, Leandro Trossard and Jurrien Timber have all withdrawn from their respective national squads during the upcoming international break.
Following the news that Ben White has replaced Ebere Eze in the England squad for their upcoming friendlies against Uruguay and Japan, the quartet have also been ruled out of representing their countries over the next fortnight due to physical issues.
Central defensive partners William and Gabriel were set to face off as France and Brazil meet in friendly action in Boston on Thursday, before Les Bleus tackle Colombia in Washington the following Sunday.