Kentucky opened as a 2.5-point favorite over Santa Clara shortly after the NCAA Tournament bracket was announced.
Kentucky opens as a 2.5 point favorite in the first round game vs Santa Clara on @DKSportsbook pic.twitter.com/DKRIoOSAxy
— Drew Franklin (@DrewFranklinKSR) March 15, 2026
FanDuel has the Cats favored by 3.5 points: The game will tip off at noon on Friday.