The 20:00 GMT kick-off at the Vitality Stadium comes on the back of Sunday's 3-1 victory at home to Aston Villa, and is our final game before the March international break.
Keep reading for everything you need to know in the build-up, including how to watch and follow the action on the south coast...
Friday's fixture will be live to watch in the UK on Sky Sports Main Event, Sky Sports Premier League and Sky Sports Ultra HDR.
Across club channels, MUTV subscribers will able to enjoy an hour of exclusive build-up and our Matchday Review post-game show, either side of live radio commentary.